Florence, South Carolina is a great overnight stop! Why? Consider this… you’ve traveled all day, you’re tired, hungry, the kids are wired… you get the picture. What you really need right about then is that perfect overnight stop… an exit where you feel safe and comfortable… an exit with a good mix of accommodations and a variety of eating places… not just fast food. And, maybe a little shopping later before you get back to the motel. The next morning you can gas up nearby and head out. Everything you need conveniently located right off the exit! That’s what makes Florence, South Carolina a great overnight stop!
About Florence, South Carolina…
Florence is a city in and the county seat of Florence County, South Carolina. It lies at the intersection of Interstates 20 and 95 and is the eastern terminus of the former. It is the primary city within the Florence metropolitan area. The area forms the core of the historical “Pee Dee” region of South Carolina, which includes the eight counties of northeastern South Carolina, along with sections of southeastern North Carolina.[5] As of the 2020 census, the population of Florence was 39,899.
Florence is one of the major cities in South Carolina. In 1965, Florence was named an All-American City, presented by the National Civic League. The city was founded as a railroad hub and became the junction of three major railroad systems, including the Wilmington and Manchester, the Northeastern, and the Cheraw and Darlington. wikipedia
Places to Stay in Florence, South Carolina…

This I-95 exit offers a relatively impressive choice of lodging options that cater to all preferences and budgets. From well-known hotel chains providing essential comforts to charming bed-and-breakfasts showcasing local hospitality, I-95 travelers can easily find their perfect overnight stay once they discover this exit.
This I-95 exit in Florence, South Carolina includes;
Baymont by Wyndham, Best Western Inn, Clarion Inn & Suites, Comfort Suites, Country Inn & Suites, Days Inn, EconoLodge, Hampton Inn & Suites, Howard Johnson by Wyndham, La Quinta Inn & Suites by Wyndham, MainStay Suites, Mictotel Inn & Suites by Wyndham, Motel 6, Park Inn by Radisson, Red Roof Inn, Sleep Inn, Studio 6, Suburban Studios, Super 8, and Tru by Hilton
For additional lodging options in the Florence area, click here.
Places to Eat in Florence, South Carolina…

At this I-95 exit in Florence, you’ll find an impressive number of dining options that cater to a multitude of tastes and preferences. From cozy cafes to upscale eateries, the selection is diverse enough to satisfy both casual diners and gourmet enthusiasts alike. Whether you’re craving classic American comfort food, authentic Italian pasta, spicy Mexican dishes, or fresh seafood delicacies, there’s a restaurant waiting for you, no matter what you’re looking for. This is a perfect stop for families, travelers, and food lovers on the go.
Options at this exit include: Arby’s, Cinnabon, Cook Out, Cracker Barrel Old Country Store, Dickey’s Barbeque Pit, Dunkin Donuts, Eliza’s Vegan Café, Fatz Cafe, Hardee’s, Jersey Mike’s Subs, Julia Belle’s, Krispy Kreme, McDonald’s, PJ Fresh Marketplace, Quincy’s Family Steakhouse, Pho An Vietnamese, Popeye’s Louisiana Kitchen, Ruby Tuesday, Shoney’s, Starbucks, Thunderbird Country Buffet, Waffle House, Wendy’s, and Zaxby’s Chicken Fingers & Buffalo Wings
Places to Shop in Florence, South Carolina…
Shopping is quite thin at this exit but you will find Young’s Premium Foods here.
Fuel Up and Head Out…
A good selection of discount gas stations is available from this exit. These include: BP, Exxon, Mobil, Pilot Travel Center, Raceway, Shell, and T/A Travel Center
More…
29 miles north is Dillon, SC, another recommended stopover exit.
66 miles south is Santee, SC, another recommended stopover exit.
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Drop down to Exit 160 for a great dining experience at Red Bone Alley restaurant… within easy reach of I-95… behind the Piggly Wiggly