South Carolina I-95 Lodging | Hotels & Motels Along I-95

South Carolina I-95 Lodging Next Right | I-95 Exit Guide

South Carolina’s portion of I-95 begins in Hammer, at the South Carolina-North Carolina border and runs approximately 199 miles (320 km) south to the South Carolina-Georgia border in Hardeeville. 

Lodging located within 1/2 mile of an I-95 exit is listed below. These South Carolina I-95 lodging listings run north to south. Individual exit descriptions show intersecting routes and cities and towns accessible from that exit.

ExitDescriptionExit Services
1A/BUS 301, US 501, Dillon
193Radford Boulevard, SC 9, SC 57, Dillon, Little RockBest Value Inn
Comfort Inn
Days Inn
EconoLodge
Hampton Inn
Holiday Inn Express
Howard Johnson
Knights Inn
Ramada Limited
Super 8
190SC 34, Dillon
181BSC 38 West
181ASC 38 East, Latta, Marion
170North Williston Road, SC 327, SC 26, Marion, Myrtle Beach
169TV Road, Quimby, FlorenceAmerica’s Best Value Inn
Park Inn International
Quality Inn
Rodeway Inn
164West Lucas Street, US 52, Florence, DarlingtonBaymont by Wyndham, Best Western Inn, Clarion Inn & Suites, Comfort Suites, Country Inn & Suites, Days Inn, EconoLodge, Florence Travelhouse Inn, Hampton Inn & Suites, Howard Johnson by Wyndham, Knights Inn, La Quinta Inn & Suites by Wyndham, MainStay Suites, Mictotel Inn & Suites by Wyndham, Motel 6, Park Inn by Raddison, Red Roof Inn, Sleep Inn, Studio 6, Suburban Studios, Super 8, Tru by Hilton
160BI-20 West, Columbia
160AI-20 East, FlorenceCourtyard Inn
Fairfield Inn
Hampton Inn & Suites
Hilton Garden Inn
Holiday Inn Express
Red Roof Inn
Residence Inn
SpringHill Suites
TownePlace Suites
ExitDescriptionExit Services
157West Palmetto Street, US 76, Florence, TimmonsvilleDays Inn
Howard Johnson Express Inn & Suites
Ramada Inn
Swampfox Inn
Travelodge
Tree Top Inn
Young’s Plantation Inn
153Honda Way
150Cale Yarborough Highway, SC 403, Sardis, TimmonsvilleBudget Inn
Econolodge
146Lynches River Road, SC 341, Olanta, LynchburgRelax Inn
141SC 53, SC 58, Shiloh
135Myrtle Beach Highway, US 378, Turbeville, SumterDays Inn
Knights Inn
132Black River Road, SC 527, Sardinia, Bishopville
122Main Street, US 521, Alcolu, Sumter
119Paxville Highway, SC 261, Manning, PaxvilleBest Western Palmetto Inn
Comfort Inn
Guest House Inn & Suites
Hampton Inn
Holiday Inn Express
Manning Economy Inn
Ramada Limited
Super 8
Thunderbird Inn
Travelodge
115Alex Harvin Highway, US 301, ManningCarolina Inn
Days Inn
Econolodge
Sunset Inn
Traveler’s Inn
ExitDescriptionExit Services
108Buff Boulevard, SR 102, SummertonAmerica’s Best Value Inn
Days Inn
Knights Inn
102St. Paul Road, US 15, US 301, Road 400, North Santee
98Old Number 6 Highway, SC 6, Eutawville, SanteeBaymont by Wyndham, Best Western Plus, Comfort Inn and Suites, Econo Lodge, Fairfield Inn and Suites, Hampton Inn, Holiday Inn, Quality Inn and Suites, Red Roof Inn, Rodeway Inn, Super 8 by Wyndham, Travelodge by Wyndham, Tru by Hilton
97US 301, Orangeburg
93Bass Drive US 15, Santee, Elloree
90Old State Road, US 176, Holly Hill, Cameron
86BI-26 West, Columbia
86AI-26 East, Charleston
82US 178, Harleyville, BowmanPeach Tree Inn
77Jim Bilton Boulevard, US 78, St. George, BranchvilleAmericas Best Value Inn
Best Value Inn
Best Western
Comfort Inn
Days Inn
EconoLodge
Economy Inn of America
Holiday Inn
Quality Inn
St. George Motor Inn
Southern Inn
Super 8
ExitDescriptionExit Services
68Augusta Highway, SC 61, Canadys, Bamberg
62McLeod Road, Road 34
57Bells Highway, SC 64, WalterboroCarolina Lodge, Sleep Inn, Super 8 by Wyndham, Travelodge by Wyndham
53Sniders Highway, SC 63, To US 17 Alt., WalterboroBest Western
Comfort Inn & Suites
Days Inn
Deluxe Inn
EconoLodge
Hampton Inn
Holiday Inn Express Hotel & Suites
Howard Johnson
Microtel
Quality Inn & Suites
Ramada Inn
Town & Country Inn
42Low Country Highway, US 21, Beaufort, Yemassee
38SC 68, Yemassee, HamptonPalmetto Lodge
Super 8
33Kings Highway, US 17, Charleston, BeaufortBest Western
Days Inn
Holiday Inn Express
Knights Inn
28SC 462, Coosawhatchie
22Jacob Smart Boulevard, US 17 South, RidgelandPlantation Inn
21US 278, Ridgeland, Hilton Head IslandComfort Inn
Days Inn
Ramada Limited
ExitDescriptionExit Services
18US 17, Road 13, Ridgeland
8Road 88, BeaufortDays Inn by Wyndham, Fairfield by Marriott Inn & Suites, Hampton Inn By Hilton, Holiday Inn Express & Suites
5US 17, US 321, Hardeeville, EstilleBest Western Plus Hardeeville Inn & Suites, Days Inn by Wyndham, Deluxe Inn, Econo Lodge, Economy Inn, Quality Inn & Suites, Red Roof Inn, Sleep Inn,Super 8 by Wyndham, Travelodge by Wyndham

About Our I-95 Exit Listings

It’s always nice to know what’s up ahead at the next exit. That’s why we’ve meticulously curated this comprehensive guide. Our detailed exit service listings cover every I-95 exit, in every state from Maine to Florida, ensuring travelers are well-informed about essential I-95 exit amenities such as food, lodging, camping and rest area options.

Beginning at the Canadian border in Maine and ending at the junction of U.S. Route 1 in Miami, Florida, our listings are organized by state and I-95 exit numbers. This structured approach allows travelers to plan their journeys efficiently, knowing exactly what services are available at each exit along the way.

Whether you’re a frequent traveler or taking a long-distance road trip, our expertly compiled guide gives you all the tools you’ll need to make informed decisions, and improve your travel experience. Stay informed and prepared with our I-95 exit service listings, designed to ensure your journey is as smooth and seamless as possible.


The I-95 Exit Guide is the Internet’s largest and most complete website dedicated to Interstate 95 travelers. Find detailed exit service listings… lodging, camping, food, gas and more for every exit from Maine to Florida!

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Traveling another route? Visit our growing family of exit guides:  I-4 Exit GuideI-5 Exit GuideI-10 Exit GuideI-75 Exit GuideI-80 Exit Guide and I-95 Exit Guide. Detailed exit service listings… discount lodging, camping, food, gas and more for every exit along the way!